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Concerted and differential actions of two enzymatic domains underlie Rad5 contributions to DNA damage tolerance
Many genome maintenance factors have multiple enzymatic activities. In most cases, how their distinct activities functionally relate with each other is unclear. Here we examined the conserved budding yeast Rad5 protein that has both ubiquitin ligase and DNA helicase activities. The Rad5 ubiquitin li...
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Publicat a: | Nucleic Acids Res |
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Autors principals: | , , , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Oxford University Press
2015
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4357696/ https://ncbi.nlm.nih.gov/pubmed/25690888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv004 |
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