Concerted and differential actions of two enzymatic domains underlie Rad5 contributions to DNA damage tolerance

Many genome maintenance factors have multiple enzymatic activities. In most cases, how their distinct activities functionally relate with each other is unclear. Here we examined the conserved budding yeast Rad5 protein that has both ubiquitin ligase and DNA helicase activities. The Rad5 ubiquitin li...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Choi, Koyi, Batke, Sabrina, Szakal, Barnabas, Lowther, Jonathan, Hao, Fanfan, Sarangi, Prabha, Branzei, Dana, Ulrich, Helle D., Zhao, Xiaolan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2015
Aiheet:
Genome Integrity, Repair and Replication
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357696/
https://ncbi.nlm.nih.gov/pubmed/25690888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv004
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