Esc2 promotes Mus81 complex-activity via its SUMO-like and DNA binding domains

Replication across damaged DNA templates is accompanied by transient formation of sister chromatid junctions (SCJs). Cells lacking Esc2, an adaptor protein containing no known enzymatic domains, are defective in the metabolism of these SCJs. However, how Esc2 is involved in the metabolism of SCJs re...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Sebesta, Marek, Urulangodi, Madhusoodanan, Stefanovie, Barbora, Szakal, Barnabas, Pacesa, Martin, Lisby, Michael, Branzei, Dana, Krejci, Lumir
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224511/
https://ncbi.nlm.nih.gov/pubmed/27694623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw882
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