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Premature Cdk1/Cdc5/Mus81 pathway activation induces aberrant replication and deleterious crossover

The error-free DNA damage tolerance (DDT) pathway is crucial for replication completion and genome integrity. Mechanistically, this process is driven by a switch of templates accompanied by sister chromatid junction (SCJ) formation. Here, we asked if DDT intermediate processing is temporarily regula...

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Detalhes bibliográficos
Main Authors: Szakal, Barnabas, Branzei, Dana
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630363/
https://ncbi.nlm.nih.gov/pubmed/23531881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.67
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