A Systems Biology Approach Reveals the Dose- and Time-Dependent Effect of Primary Human Airway Epithelium Tissue Culture After Exposure to Cigarette Smoke In Vitro

To establish a relevant in vitro model for systems toxicology-based mechanistic assessment of environmental stressors such as cigarette smoke (CS), we exposed human organotypic bronchial epithelial tissue cultures at the air liquid interface (ALI) to various CS doses. Previously, we compared in vitr...

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Detalles Bibliográficos
Publicado en:Bioinform Biol Insights
Autores principales: Mathis, Carole, Gebel, Stephan, Poussin, Carine, Belcastro, Vincenzo, Sewer, Alain, Weisensee, Dirk, Hengstermann, Arnd, Ansari, Sam, Wagner, Sandra, Peitsch, Manuel C, Hoeng, Julia
Formato: Artigo
Lenguaje:Inglês
Publicado: Libertas Academica 2015
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357630/
https://ncbi.nlm.nih.gov/pubmed/25788831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BBI.S19908
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