Systematic Verification of Upstream Regulators of a Computable Cellular Proliferation Network Model on Non-Diseased Lung Cells Using a Dedicated Dataset

We recently constructed a computable cell proliferation network (CPN) model focused on lung tissue to unravel complex biological processes and their exposure-related perturbations from molecular profiling data. The CPN consists of edges and nodes representing upstream controllers of gene expression...

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Detalhes bibliográficos
Main Authors: Belcastro, Vincenzo, Poussin, Carine, Gebel, Stephan, Mathis, Carole, Schlage, Walter K., Lichtner, Rosemarie B., Quadt-Humme, Sibille, Wagner, Sandra, Hoeng, Julia, Peitsch, Manuel C.
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733638/
https://ncbi.nlm.nih.gov/pubmed/23926424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BBI.S12167
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