A Systems Biology Approach Reveals the Dose- and Time-Dependent Effect of Primary Human Airway Epithelium Tissue Culture After Exposure to Cigarette Smoke In Vitro

To establish a relevant in vitro model for systems toxicology-based mechanistic assessment of environmental stressors such as cigarette smoke (CS), we exposed human organotypic bronchial epithelial tissue cultures at the air liquid interface (ALI) to various CS doses. Previously, we compared in vitr...

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Bibliographic Details
Published in:Bioinform Biol Insights
Main Authors: Mathis, Carole, Gebel, Stephan, Poussin, Carine, Belcastro, Vincenzo, Sewer, Alain, Weisensee, Dirk, Hengstermann, Arnd, Ansari, Sam, Wagner, Sandra, Peitsch, Manuel C, Hoeng, Julia
Format: Artigo
Language:Inglês
Published: Libertas Academica 2015
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357630/
https://ncbi.nlm.nih.gov/pubmed/25788831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BBI.S19908
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