A Systems Biology Approach Reveals the Dose- and Time-Dependent Effect of Primary Human Airway Epithelium Tissue Culture After Exposure to Cigarette Smoke In Vitro

To establish a relevant in vitro model for systems toxicology-based mechanistic assessment of environmental stressors such as cigarette smoke (CS), we exposed human organotypic bronchial epithelial tissue cultures at the air liquid interface (ALI) to various CS doses. Previously, we compared in vitr...

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Библиографические подробности
Опубликовано в: :Bioinform Biol Insights
Главные авторы: Mathis, Carole, Gebel, Stephan, Poussin, Carine, Belcastro, Vincenzo, Sewer, Alain, Weisensee, Dirk, Hengstermann, Arnd, Ansari, Sam, Wagner, Sandra, Peitsch, Manuel C, Hoeng, Julia
Формат: Artigo
Язык:Inglês
Опубликовано: Libertas Academica 2015
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357630/
https://ncbi.nlm.nih.gov/pubmed/25788831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BBI.S19908
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