A Systems Biology Approach Reveals the Dose- and Time-Dependent Effect of Primary Human Airway Epithelium Tissue Culture After Exposure to Cigarette Smoke In Vitro

To establish a relevant in vitro model for systems toxicology-based mechanistic assessment of environmental stressors such as cigarette smoke (CS), we exposed human organotypic bronchial epithelial tissue cultures at the air liquid interface (ALI) to various CS doses. Previously, we compared in vitr...

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Detalhes bibliográficos
Publicado no:Bioinform Biol Insights
Main Authors: Mathis, Carole, Gebel, Stephan, Poussin, Carine, Belcastro, Vincenzo, Sewer, Alain, Weisensee, Dirk, Hengstermann, Arnd, Ansari, Sam, Wagner, Sandra, Peitsch, Manuel C, Hoeng, Julia
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357630/
https://ncbi.nlm.nih.gov/pubmed/25788831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BBI.S19908
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