טוען...
shRNA library screening identifies nucleocytoplasmic transport as a mediator of BCR-ABL1 kinase-independent resistance
The mechanisms underlying tyrosine kinase inhibitor (TKI) resistance in chronic myeloid leukemia (CML) patients lacking explanatory BCR-ABL1 kinase domain mutations are incompletely understood. To identify mechanisms of TKI resistance that are independent of BCR-ABL1 kinase activity, we introduced a...
שמור ב:
הוצא לאור ב: | Blood |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , |
פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
American Society of Hematology
2015
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4357584/ https://ncbi.nlm.nih.gov/pubmed/25573989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-08-588855 |
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