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Combined PKC and MEK inhibition for treating metastatic uveal melanoma
Uveal melanoma (UM) is the most common primary intraocular malignancy and the second most common form of melanoma. UM has a strong tendency for metastatic disease, and no effective treatments have yet been identified. Activating oncogenic mutations are commonly found in GNAQ and GNA11 in UM, and inh...
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| Publicat a: | Oncogene |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4356624/ https://ncbi.nlm.nih.gov/pubmed/24413085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.555 |
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