Wird geladen...

Combined PKC and MEK inhibition for treating metastatic uveal melanoma

Uveal melanoma (UM) is the most common primary intraocular malignancy and the second most common form of melanoma. UM has a strong tendency for metastatic disease, and no effective treatments have yet been identified. Activating oncogenic mutations are commonly found in GNAQ and GNA11 in UM, and inh...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Oncogene
Hauptverfasser: Sagoo, MS, Harbour, JW, Stebbing, J, Bowcock, AM
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356624/
https://ncbi.nlm.nih.gov/pubmed/24413085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.555
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!