Aging-dependent alterations in gene expression and a mitochondrial signature of responsiveness to human influenza vaccination

To elucidate gene expression pathways underlying age-associated impairment in influenza vaccine response, we screened young (age 21-30) and older (age ≥65) adults receiving influenza vaccine in two consecutive seasons and identified those with strong or absent response to vaccine, including a subset...

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Vydáno v:Aging (Albany NY)
Hlavní autoři: Thakar, Juilee, Mohanty, Subhasis, West, A. Phillip, Joshi, Samit R., Ueda, Ikuyo, Wilson, Jean, Meng, Hailong, Blevins, Tamara P., Tsang, Sui, Trentalange, Mark, Siconolfi, Barbara, Park, Koonam, Gill, Thomas M., Belshe, Robert B., Kaech, Susan M., Shadel, Gerald S., Kleinstein, Steven H., Shaw, Albert C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356402/
https://ncbi.nlm.nih.gov/pubmed/25596819
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