Aging-dependent alterations in gene expression and a mitochondrial signature of responsiveness to human influenza vaccination

To elucidate gene expression pathways underlying age-associated impairment in influenza vaccine response, we screened young (age 21-30) and older (age ≥65) adults receiving influenza vaccine in two consecutive seasons and identified those with strong or absent response to vaccine, including a subset...

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Foilsithe in:Aging (Albany NY)
Main Authors: Thakar, Juilee, Mohanty, Subhasis, West, A. Phillip, Joshi, Samit R., Ueda, Ikuyo, Wilson, Jean, Meng, Hailong, Blevins, Tamara P., Tsang, Sui, Trentalange, Mark, Siconolfi, Barbara, Park, Koonam, Gill, Thomas M., Belshe, Robert B., Kaech, Susan M., Shadel, Gerald S., Kleinstein, Steven H., Shaw, Albert C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2015
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356402/
https://ncbi.nlm.nih.gov/pubmed/25596819
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