Impact of Aging and HIV Infection on the Function of the C-Type Lectin Receptor MINCLE in Monocytes

Both aging and HIV infection are associated with an enhanced pro-inflammatory environment that contributes to impaired immune responses and is mediated in part by innate immune pattern-recognition receptors. MINCLE is a C-type lectin receptor that recognizes trehalose-6,6ʹ-dimycolate or “cord factor...

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Bibliografske podrobnosti
izdano v:J Gerontol A Biol Sci Med Sci
Main Authors: Zapata, Heidi J, Van Ness, Peter H, Avey, Stefan, Siconolfi, Barbara, Allore, Heather G, Tsang, Sui, Wilson, Jean, Barakat, Lydia, Mohanty, Subhasis, Shaw, Albert C
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
The Journal of Gerontology: Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521921/
https://ncbi.nlm.nih.gov/pubmed/30239628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/gly209
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