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NRF2-driven miR-125B1 and miR-29B1 transcriptional regulation controls a novel anti-apoptotic miRNA regulatory network for AML survival

Transcription factor NRF2 is an important regulator of oxidative stress. It is involved in cancer progression, and has abnormal constitutive expression in acute myeloid leukaemia (AML). Posttranscriptional regulation by microRNAs (miRNAs) can affect the malignant phenotype of AML cells. In this stud...

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Publicat a:Cell Death Differ
Autors principals: Shah, N M, Zaitseva, L, Bowles, K M, MacEwan, D J, Rushworth, S A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356334/
https://ncbi.nlm.nih.gov/pubmed/25323587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.152
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