NRF2-driven miR-125B1 and miR-29B1 transcriptional regulation controls a novel anti-apoptotic miRNA regulatory network for AML survival

Transcription factor NRF2 is an important regulator of oxidative stress. It is involved in cancer progression, and has abnormal constitutive expression in acute myeloid leukaemia (AML). Posttranscriptional regulation by microRNAs (miRNAs) can affect the malignant phenotype of AML cells. In this stud...

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Udgivet i:Cell Death Differ
Main Authors: Shah, N M, Zaitseva, L, Bowles, K M, MacEwan, D J, Rushworth, S A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356334/
https://ncbi.nlm.nih.gov/pubmed/25323587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.152
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