Attenuation of dexamethasone-induced cell death in multiple myeloma is mediated by miR-125b expression

Dexamethasone is a key front-line chemotherapeutic for B-cell malignant multiple myeloma (MM). Dexamethasone modulates MM cell survival signaling but fails to induce marked cytotoxicity when used as a monotherapy. We demonstrate here the mechanism behind this insufficient responsiveness of MM cells...

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Detaylı Bibliyografya
Asıl Yazarlar: Murray, Megan Y., Rushworth, Stuart A., Zaitseva, Lyubov, Bowles, Kristian M., MacEwan, David J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2013
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737316/
https://ncbi.nlm.nih.gov/pubmed/23759586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25251
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