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Attenuation of dexamethasone-induced cell death in multiple myeloma is mediated by miR-125b expression
Dexamethasone is a key front-line chemotherapeutic for B-cell malignant multiple myeloma (MM). Dexamethasone modulates MM cell survival signaling but fails to induce marked cytotoxicity when used as a monotherapy. We demonstrate here the mechanism behind this insufficient responsiveness of MM cells...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Landes Bioscience
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3737316/ https://ncbi.nlm.nih.gov/pubmed/23759586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25251 |
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