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NRF2-driven miR-125B1 and miR-29B1 transcriptional regulation controls a novel anti-apoptotic miRNA regulatory network for AML survival

Transcription factor NRF2 is an important regulator of oxidative stress. It is involved in cancer progression, and has abnormal constitutive expression in acute myeloid leukaemia (AML). Posttranscriptional regulation by microRNAs (miRNAs) can affect the malignant phenotype of AML cells. In this stud...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Differ
Hoofdauteurs: Shah, N M, Zaitseva, L, Bowles, K M, MacEwan, D J, Rushworth, S A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356334/
https://ncbi.nlm.nih.gov/pubmed/25323587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.152
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