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Human Lymphoid Translocation Fragile Zones Are Hypomethylated and Have Accessible Chromatin
Chromosomal translocations are a hallmark of hematopoietic malignancies. CG motifs within translocation fragile zones (typically 20 to 600 bp in size) are prone to chromosomal translocation in lymphomas. Here we demonstrate that the CG motifs in human translocation fragile zones are hypomethylated r...
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| Vydáno v: | Mol Cell Biol |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355534/ https://ncbi.nlm.nih.gov/pubmed/25624348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01085-14 |
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