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Human Lymphoid Translocation Fragile Zones Are Hypomethylated and Have Accessible Chromatin

Chromosomal translocations are a hallmark of hematopoietic malignancies. CG motifs within translocation fragile zones (typically 20 to 600 bp in size) are prone to chromosomal translocation in lymphomas. Here we demonstrate that the CG motifs in human translocation fragile zones are hypomethylated r...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Lu, Zhengfei, Lieber, Michael R., Tsai, Albert G., Pardo, Carolina E., Müschen, Markus, Kladde, Michael P., Hsieh, Chih-Lin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355534/
https://ncbi.nlm.nih.gov/pubmed/25624348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01085-14
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