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Human Lymphoid Translocation Fragile Zones Are Hypomethylated and Have Accessible Chromatin
Chromosomal translocations are a hallmark of hematopoietic malignancies. CG motifs within translocation fragile zones (typically 20 to 600 bp in size) are prone to chromosomal translocation in lymphomas. Here we demonstrate that the CG motifs in human translocation fragile zones are hypomethylated r...
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| Publicado no: | Mol Cell Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355534/ https://ncbi.nlm.nih.gov/pubmed/25624348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01085-14 |
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