Both CpG Methylation and Activation-Induced Deaminase Are Required for the Fragility of the Human bcl-2 Major Breakpoint Region: Implications for the Timing of the Breaks in the t(14;18) Translocation

The t(14;18) chromosomal translocation typically involves breakage at the bcl-2 major breakpoint region (MBR) to cause human follicular lymphoma. A theory to explain the striking propensity of the MBR breaks at three CpG clusters within the 175-bp MBR region invoked activation-induced deaminase (AID...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Cui, Xiaoping, Lu, Zhengfei, Kurosawa, Aya, Klemm, Lars, Bagshaw, Andrew T., Tsai, Albert G., Gemmell, Neil, Müschen, Markus, Adachi, Noritaka, Hsieh, Chih-Lin, Lieber, Michael R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2013
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623081/
https://ncbi.nlm.nih.gov/pubmed/23263985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01436-12
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller