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Methylation of CpG sites in BCL2 major breakpoint region and the increase of BCL2/JH translocation with aging

The BCL2 breakage mechanism has been shown to be highly dependent on DNA methylation at the major breakpoint region (MBR) CpG sites. We recently described an increased frequency of BCL2/ JH translocation with aging. It is known that methylation levels change with aging. The present study aimed to de...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Age (Dordr)
Egile Nagusiak: Martin-Guerrero, Idoia, de Prado, Elena, Ardanaz, Maite, Martin-Arruti, Maialen, Garcia-Orad, Cristina, Guerra, Isabel, Ruiz, Irune, Zabalza, Iñaki, Garcia-Orad, Africa
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer International Publishing 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005837/
https://ncbi.nlm.nih.gov/pubmed/26335622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-015-9834-5
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