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Methylation of the nonhomologous end joining repair pathway genes does not explain the increase of translocations with aging

Chromosome translocations are especially frequent in human lymphomas and leukemias but are insufficient to drive carcinogenesis. Indeed, several of the so-called tumor specific translocations have been detected in peripheral blood of healthy individuals, finding a higher frequency of some of them wi...

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Detalhes bibliográficos
Publicado no:Age (Dordr)
Main Authors: Martín-Guerrero, Idoia, de Prado, Elena, Lopez-Lopez, Elixabet, Ardanaz, Maite, Vitoria, Juan Carlos, Parada, Luis A., García-Orad, Cristina, García-Orad, Africa
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233023/
https://ncbi.nlm.nih.gov/pubmed/25399073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-014-9730-4
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