The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations

We have used spectral karyotyping to assess potential roles of three different components of the nonhomologous DNA end-joining pathway in the maintenance of genomic stability in mouse embryonic fibroblasts (MEFs). MEFs homozygous for mutations that inactivate either DNA ligase IV (Lig4) or Ku70 disp...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Ferguson, David O., Sekiguchi, JoAnn M., Chang, Sandy, Frank, Karen M., Gao, Yijie, DePinho, Ronald A., Alt, Frederick W.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2000
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC18682/
https://ncbi.nlm.nih.gov/pubmed/10823907
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars