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Nonhomologous DNA End Joining in Cell-Free Extracts

Among various DNA damages, double-strand breaks (DSBs) are considered as most deleterious, as they may lead to chromosomal rearrangements and cancer when unrepaired. Nonhomologous DNA end joining (NHEJ) is one of the major DSB repair pathways in higher organisms. A large number of studies on NHEJ a...

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Autors principals: Sheetal Sharma, Sathees C. Raghavan
Format: Artigo
Idioma:Inglês
Publicat: Wiley 2010-01-01
Col·lecció:Journal of Nucleic Acids
Accés en línia:http://dx.doi.org/10.4061/2010/389129
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