The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations

We have used spectral karyotyping to assess potential roles of three different components of the nonhomologous DNA end-joining pathway in the maintenance of genomic stability in mouse embryonic fibroblasts (MEFs). MEFs homozygous for mutations that inactivate either DNA ligase IV (Lig4) or Ku70 disp...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Ferguson, David O., Sekiguchi, JoAnn M., Chang, Sandy, Frank, Karen M., Gao, Yijie, DePinho, Ronald A., Alt, Frederick W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2000
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC18682/
https://ncbi.nlm.nih.gov/pubmed/10823907
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller