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Mechanism of Fragility at BCL2 Gene Minor Breakpoint Cluster Region during t(14;18) Chromosomal Translocation

The t(14;18) translocation in follicular lymphoma is one of the most common chromosomal translocations. Breaks in chromosome 18 are localized at the 3′-UTR of BCL2 gene or downstream and are mainly clustered in either the major breakpoint region or the minor breakpoint cluster region (mcr). The reco...

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書目詳細資料
Main Authors: Nambiar, Mridula, Raghavan, Sathees C.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308786/
https://ncbi.nlm.nih.gov/pubmed/22275374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.307363
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