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G-Quadruplex Structures Formed at the HOX11 Breakpoint Region Contribute to Its Fragility during t(10;14) Translocation in T-Cell Leukemia

The t(10;14) translocation involving the HOX11 gene is found in several T-cell leukemia patients. Previous efforts to determine the causes of HOX11 fragility were not successful. The role of non-B DNA structures is increasingly becoming an important cause of genomic instability. In the present study...

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Detaylı Bibliyografya
Asıl Yazarlar: Nambiar, Mridula, Srivastava, Mrinal, Gopalakrishnan, Vidya, Sankaran, Sritha K., Raghavan, Sathees C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811900/
https://ncbi.nlm.nih.gov/pubmed/24001773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00540-13
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