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Human Chromosomal Translocations at CpG Sites and a Theoretical Basis for their Lineage and Stage Specificity
We have assembled, annotated, and analyzed a database of over 1700 breakpoints from the most common chromosomal rearrangements in human leukemias and lymphomas. Using this database, we show that although the CpG dinucleotide constitutes only 1% of the human genome, it accounts for 40–70% of breakpoi...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2642632/ https://ncbi.nlm.nih.gov/pubmed/19070581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.10.035 |
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