Associations Between Biomarkers and Age in the Presenilin 1 E280A Autosomal Dominant Alzheimer Disease Kindred A Cross-sectional Study

IMPORTANCE: Age-associated changes in brain imaging and fluid biomarkers are characterized and compared in presenilin 1 (PSEN1) E280A mutation carriers and noncarriers from the world’s largest known autosomal dominant Alzheimer disease (AD) kindred. OBJECTIVE: To characterize and compare age-associa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JAMA Neurol
Prif Awduron: Fleisher, Adam S., Chen, Kewei, Quiroz, Yakeel T., Jakimovich, Laura J., Gomez, Madelyn Gutierrez, Langois, Carolyn M., Langbaum, Jessica B. S., Roontiva, Auttawut, Thiyyagura, Pradeep, Lee, Wendy, Ayutyanont, Napatkamon, Lopez, Liliana, Moreno, Sonia, Muñoz, Claudia, Tirado, Victoria, Acosta-Baena, Natalia, Fagan, Anne M., Giraldo, Margarita, Garcia, Gloria, Huentelman, Matthew J., Tariot, Pierre N., Lopera, Francisco, Reiman, Eric M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355261/
https://ncbi.nlm.nih.gov/pubmed/25580592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2014.3314
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