Florbetapir PET analysis of amyloid-β deposition in the presenilin 1 E280A autosomal dominant Alzheimer’s disease kindred: a cross-sectional study

BACKGROUND: Fibrillar amyloid-β (Aβ) is thought to begin accumulating in the brain many years before the onset of clinical impairment in patients with Alzheimer’s disease. By assessing the accumulation of Aβ in people at risk of genetic forms of Alzheimer’s disease, we can identify how early preclin...

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Autori principali: Fleisher, Adam S, Chen, Kewei, Quiroz, Yakeel T, Jakimovich, Laura J, Gomez, Madelyn Gutierrez, Langois, Carolyn M, Langbaum, Jessica B S, Ayutyanont, Napatkamon, Roontiva, Auttawut, Thiyyagura, Pradeep, Lee, Wendy, Mo, Hua, Lopez, Liliana, Moreno, Sonia, Acosta-Baena, Natalia, Giraldo, Margarita, Garcia, Gloria, Reiman, Rebecca A, Huentelman, Matthew J, Kosik, Kenneth S, Tariot, Pierre N, Lopera, Francisco, Reiman, Eric M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515078/
https://ncbi.nlm.nih.gov/pubmed/23137949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(12)70227-2
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