T cell receptor cross-reactivity between similar foreign and self peptides influences naïve cell population size and autoimmunity

T cell receptor (TCR) cross-reactivity between major histocompatibility complex II (MHCII)-binding self and foreign peptides could influence the naïve CD4(+) T cell repertoire and autoimmunity. We found that nonamer peptides that bind to the same MHCII molecule only need to share five amino acids to...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Immunity
Main Authors: Nelson, Ryan W., Beisang, Daniel, Tubo, Noah J., Dileepan, Thamotharampillai, Wiesner, Darin L., Nielsen, Kirsten, Wüthrich, Marcel, Klein, Bruce S., Kotov, Dmitri I., Spanier, Justin A., Fife, Brian T., Moon, James J., Jenkins, Marc K.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355167/
https://ncbi.nlm.nih.gov/pubmed/25601203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.12.022
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker