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Naïve B cells with high-avidity germline-encoded antigen receptors produce persistent IgM(+) and transient IgG(+) memory B cells
Although immune memory often lasts for life, this is not the case for certain vaccines in some individuals. We sought a mechanism for this phenomenon by studying B cell responses to phycoerythrin (PE). PE immunization of mouse strains with Igh(b) immunoglobulin (Ig) variable heavy chain (V(H)) genes...
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| 出版年: | Immunity |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6052797/ https://ncbi.nlm.nih.gov/pubmed/29884459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.04.019 |
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