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Intrinsic differences in the initiation of B cell receptor signaling favor responses of human IgG(+) memory B cells over IgM(+) naïve B cells
The acquisition of long-lived memory B cells (MBCs) is critical for the defense against many infectious diseases. Despite their importance, little is known about how antigens (Ags) trigger human MBCs, even though our understanding of the molecular basis of Ag activation of B cells in model systems h...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311745/ https://ncbi.nlm.nih.gov/pubmed/22379037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102322 |
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