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Cellular dynamics of memory B cell populations: IgM(+) and IgG(+) memory B cells persist indefinitely as quiescent cells()

Despite their critical role in long-term immunity, the lifespan of individual memory B cells remains poorly defined. Using a tetracycline-regulated pulse-chase system, we measured population turnover rates and individual half-lives of pre-established antigen-induced immunoglobulin (Ig) class-switche...

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Vydáno v:J Immunol
Hlavní autoři: Jones, Derek D., Wilmore, Joel R., Allman, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637268/
https://ncbi.nlm.nih.gov/pubmed/26438523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501365
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