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T cell-dependent IgM Memory B Cells Generated During Bacterial Infection are Required for IgG Responses to Antigen Challenge

Immunological memory has long considered to be harbored in B cells that express high affinity class-switched IgG. IgM-positive memory B cells can also be generated following immunization, although their physiological role has been unclear. Here we show that bacterial infection elicited a relatively...

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Detalhes bibliográficos
Main Authors: Yates, Jennifer L., Racine, Rachael, McBride, Kevin M., Winslow, Gary M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720767/
https://ncbi.nlm.nih.gov/pubmed/23804710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300062
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