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Epithelial NAIPs protect against colonic tumorigenesis
NLR family apoptosis inhibitory proteins (NAIPs) belong to both the Nod-like receptor (NLR) and the inhibitor of apoptosis (IAP) families. NAIPs are known to form an inflammasome with NLRC4, but other in vivo functions remain unexplored. Using mice deficient for all NAIP paralogs (Naip1-6(Δ/Δ)), we...
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| Pubblicato in: | J Exp Med |
|---|---|
| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4354369/ https://ncbi.nlm.nih.gov/pubmed/25732303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20140474 |
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