Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation

Ribosomal proteins (RP) regulate specific gene expression by selectively translating subsets of mRNAs. Indeed, in Diamond-Blackfan anemia and 5q(–) syndrome, mutations in RP genes lead to a specific defect in erythroid gene translation and cause anemia. Little is known about the molecular mechanisms...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Chennupati, Vijaykumar, Veiga, Diogo F.T., Maslowski, Kendle M., Andina, Nicola, Tardivel, Aubry, Yu, Eric Chi-Wang, Stilinovic, Martina, Simillion, Cedric, Duchosal, Michel A., Quadroni, Manfredo, Roberts, Irene, Sankaran, Vijay G., MacDonald, H. Robson, Fasel, Nicolas, Angelillo-Scherrer, Anne, Schneider, Pascal, Hoang, Trang, Allam, Ramanjaneyulu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873846/
https://ncbi.nlm.nih.gov/pubmed/29408805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94956
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