Claudin-7 expression induces mesenchymal to epithelial transformation (MET) to inhibit colon tumorigenesis

In normal colon, claudin-7 is one of the highly expressed claudin proteins and its knockdown in mice results in altered epithelial cell homeostasis and neonatal death. Notably, dysregulation of the epithelial homeostasis potentiates oncogenic transformation and growth. However, the role of claudin-7...

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Publicado en:Oncogene
Main Authors: Bhat, AA, Pope, JL, Smith, JJ, Ahmad, R, Chen, X, Washington, MK, Beauchamp, RD, Singh, AB, Dhawan, P
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804637/
https://ncbi.nlm.nih.gov/pubmed/25500541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.385
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