Claudin-1 Regulates Intestinal Epithelial Homeostasis through the Modulation of Notch Signaling

OBJECTIVE: Claudin-1 expression is increased and dysregulated in colorectal cancer and causally associates with the dedifferentiation of colonic epithelial cells, cancer progression and metastasis. Here, we have sought to determine the role claudin-1 plays in the regulation of intestinal epithelial...

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書誌詳細
主要な著者: Pope, Jillian L., Bhat, Ajaz. A., Sharma, Ashok, Ahmad, Rizwan, Krishnan, Moorthy, Washington, Mary K., Beauchamp, Robert D., Singh, Amar B., Dhawan, Punita
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083824/
https://ncbi.nlm.nih.gov/pubmed/23766441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2012-304241
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