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Claudin-1 Regulates Intestinal Epithelial Homeostasis through the Modulation of Notch Signaling

OBJECTIVE: Claudin-1 expression is increased and dysregulated in colorectal cancer and causally associates with the dedifferentiation of colonic epithelial cells, cancer progression and metastasis. Here, we have sought to determine the role claudin-1 plays in the regulation of intestinal epithelial...

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Hlavní autoři: Pope, Jillian L., Bhat, Ajaz. A., Sharma, Ashok, Ahmad, Rizwan, Krishnan, Moorthy, Washington, Mary K., Beauchamp, Robert D., Singh, Amar B., Dhawan, Punita
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083824/
https://ncbi.nlm.nih.gov/pubmed/23766441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2012-304241
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