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Ligand-Detected Relaxation Dispersion NMR Spectroscopy: Dynamics of preQ(1)–RNA Binding
An NMR-based approach to characterizing the binding kinetics of ligand molecules to biomolecules, like RNA or proteins, by ligand-detected Carr-Purcell-Meiboom-Gill (CPMG) relaxation dispersion experiments is described. A (15)N-modified preQ(1) ligand is used to acquire relaxation dispersion experim...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4353840/ https://ncbi.nlm.nih.gov/pubmed/25403518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201409779 |
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