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Probing RNA dynamics via longitudinal exchange and CPMG relaxation dispersion NMR spectroscopy using a sensitive (13)C-methyl label
The refolding kinetics of bistable RNA sequences were studied in unperturbed equilibrium via (13)C exchange NMR spectroscopy. For this purpose a straightforward labeling technique was elaborated using a 2′-(13)C-methoxy uridine modification, which was prepared by a two-step synthesis and introduced...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3105391/ https://ncbi.nlm.nih.gov/pubmed/21252295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1361 |
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