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Probing Excited States and Activation Energy for the Integral Membrane Protein Phospholamban by NMR CPMG Relaxation Dispersion Experiments

Phospholamban (PLN) is a dynamic single-pass membrane protein that inhibits the flow of Ca(2+) ions into the sarcoplasmic reticulum (SR) of heart muscle by directly binding to and inhibiting the SR Ca(2+)ATPase (SERCA). The PLN monomer is the functionally active form that exists in equilibrium betwe...

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Detalhes bibliográficos
Main Authors: Traaseth, Nathaniel J., Veglia, Gianluigi
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328355/
https://ncbi.nlm.nih.gov/pubmed/19781521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2009.09.009
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