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Excited States of Nucleic Acids Probed by Proton Relaxation Dispersion NMR Spectroscopy

In this work an improved stable isotope labeling protocol for nucleic acids is introduced. The novel building blocks eliminate/minimize homonuclear (13)C and (1)H scalar couplings thus allowing proton relaxation dispersion (RD) experiments to report accurately on the chemical exchange of nucleic aci...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Juen, Michael Andreas, Wunderlich, Christoph Hermann, Nußbaumer, Felix, Tollinger, Martin, Kontaxis, Georg, Konrat, Robert, Hansen, D. Flemming, Kreutz, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082494/
https://ncbi.nlm.nih.gov/pubmed/27533469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201605870
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