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Excited States of Nucleic Acids Probed by Proton Relaxation Dispersion NMR Spectroscopy

In this work an improved stable isotope labeling protocol for nucleic acids is introduced. The novel building blocks eliminate/minimize homonuclear (13)C and (1)H scalar couplings thus allowing proton relaxation dispersion (RD) experiments to report accurately on the chemical exchange of nucleic aci...

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Pubblicato in:Angew Chem Int Ed Engl
Autori principali: Juen, Michael Andreas, Wunderlich, Christoph Hermann, Nußbaumer, Felix, Tollinger, Martin, Kontaxis, Georg, Konrat, Robert, Hansen, D. Flemming, Kreutz, Christoph
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082494/
https://ncbi.nlm.nih.gov/pubmed/27533469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201605870
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