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Probing Excited States and Activation Energy for the Integral Membrane Protein Phospholamban by NMR CPMG Relaxation Dispersion Experiments
Phospholamban (PLN) is a dynamic single-pass membrane protein that inhibits the flow of Ca(2+) ions into the sarcoplasmic reticulum (SR) of heart muscle by directly binding to and inhibiting the SR Ca(2+)ATPase (SERCA). The PLN monomer is the functionally active form that exists in equilibrium betwe...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3328355/ https://ncbi.nlm.nih.gov/pubmed/19781521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2009.09.009 |
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