HIF-1α Activation by Intermittent Hypoxia Requires NADPH Oxidase Stimulation by Xanthine Oxidase

Hypoxia-inducible factor 1 (HIF-1) mediates many of the systemic and cellular responses to intermittent hypoxia (IH), which is an experimental model that simulates O(2) saturation profiles occurring with recurrent apnea. IH-evoked HIF-1α synthesis and stability are due to increased reactive oxygen s...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Nanduri, Jayasri, Vaddi, Damodara Reddy, Khan, Shakil A., Wang, Ning, Makarenko, Vladislav, Semenza, Gregg L., Prabhakar, Nanduri R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353619/
https://ncbi.nlm.nih.gov/pubmed/25751622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119762
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki