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Kinetics and thermodynamics of metal-binding to histone deacetylase 8
Histone deacetylase 8 (HDAC8) was originally classified as a Zn(II)-dependent deacetylase on the basis of Zn(II)-dependent HDAC8 activity in vitro and illumination of a Zn(II) bound to the active site. However, in vitro measurements demonstrated that HDAC8 has higher activity with a bound Fe(II) tha...
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| Publicat a: | Protein Sci |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BlackWell Publishing Ltd
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4353361/ https://ncbi.nlm.nih.gov/pubmed/25516458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2623 |
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