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Ion Mobility-Mass Spectrometry Reveals Evidence of Specific Complex Formation between Human Histone Deacetylase 8 and Poly-r(C)-binding Protein 1

Histone deacetylase 8, part of a broad class of proteins responsible for regulating transcription and many other cellular processes and directly linked to a host of human disease through its mis-function, has been canonically described as a zinc-based mettalo-enzyme for many years. Recent evidence,...

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Bibliographic Details
Published in:Int J Mass Spectrom
Main Authors: Niu, Shuai, Kim, Byung Chul, Fierke, Carol A., Ruotolo, Brandon T.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624731/
https://ncbi.nlm.nih.gov/pubmed/28983190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2016.12.017
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