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Ion Mobility-Mass Spectrometry Differentiates Protein Quaternary Structures formed in Solution and in Electrospray Droplets

Electrospray ionization coupled to mass spectrometry is a key technology for determining the stoichiometries of multiprotein complexes. Despite highly accurate results for many assemblies, challenging samples can generate signals for artifact protein-protein binding born of the crowding forces prese...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Han, Linjie, Ruotolo, Brandon T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157838/
https://ncbi.nlm.nih.gov/pubmed/26075825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.5b01010
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